World's first baby born using transplanted uterus from deceased donor

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This isn't the first baby born to a woman with a uterine transplant-several have been born in Sweden, the us, and Brazil to women who received uterine transplants from live donors.

The mother was a 32-year-old woman with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome - a condition that causes female sexual reproductive organs, such as the uterus and vagina, to be underdeveloped or absent at birth. The donor was a 45-year-old woman who died of a stroke.

The recipient, who was not identified, gave birth at 35 weeks and three days by cesarean section.

The baby was born around 36 weeks of pregnancy and is "healthy and developing", along with the mother, the paper says.

This baby is the first baby born to a woman with a uterus transplanted from a deceased donor. Ten deceased donor uterus transplants had been attempted and failed in the US, Czech Republic and Turkey.

If uterus transplants ever become a run of the mill procedure, it could change the lives of many, many would-be parents. "While uterine surrogacy is legal in the USA, this offers an option, albeit an extreme and expensive one, to women who want to carry their own baby".

The baby girl was born in December 2017, but had to be closely monitored to ensure she was meeting appropriate developmental milestones.

The first birth after a womb transplant from a living donor took place in Sweden in September 2013. The live donors need to be family members of the woman and be willing to donate, as per the current practice.

The 34-year-old woman from São Paulo, Brazil, underwent the procedure in 2016 under the guidance of Dr Dani Ejzenberg and his research team at the University Hospital of Sao Paulo.

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This was the first uterine transplantation in Latin America.

The woman received five immunosuppression drugs, as well as antimicrobials, anti-blood clotting treatment and aspirin while in hospital, and immunosuppression was continued up until the woman gave birth. The possibility of successful pregnancies using deceased donors expands the possibilities for fertility. The demonstrated success of a procedure involving a deceased donor, he says, may spare live donors from undergoing risky procedures, and make transplants possible for far more women.

Doctors perform the womb transplant procedure at the hospital in Sao Paulo, Brazil Dec. 15, 2017 in this picture handout obtained today. "While uterine transplantation sounds extreme, it can be indicated in women born without a uterus, or in women who have a non-functional or surgically-absent uterus".

He said any doubts he had about the potential importance of uterus transplants were erased after meeting the mother of the first baby born after a live donor uterus transplant.

The early embryos produced by IVF treatment had been frozen and stored four months before the transplant.

But the outcomes and effects of donations from live and deceased donors are yet to be compared. The uterus was removed from recipient post that.

Researchers not involved in the study cautioned that, given all the biological constraints, the pool of potential uterus donors is actually quite small, even taking into account deceased donors.

According to data included in the new report, among infertile couples, one in 500 have uterine infertility due to factors such as birth defects, hysterectomy or infection.

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