The Pistons overwhelmed visitors Cleveland on the boards, 48-30, to overcome 20 turnovers.
A 40-point third quarter helped it erase a 16-point halftime deficit.
Cavaliers guards clearly made an effort to be more aggressive in attacking the basket early, something that Lue emphasized prior to the game. Korver led the way with 21 for Cleveland, but Detroit had an answer for every Cavs scoring run in the second half. The guards combined to score 22 of Portland's final 26 points to seal the win.
Cavaliers All-Star Kevin Love will miss Thursday night's game against the Pistons with a sore left foot, another blow to a winless Cleveland team.
Russell Westbrook had 13 points, 15 rebounds and eight assists, though only landed five for 20. He slowed down a little bit in the First Round matchup, but still finished with 23 points in Indy's Game 7 loss.More news: HUAWEI Presents the Mate 20 Series with Improved Artificial Intelligence
CJ McCollum had 22 for the Trail Blazers and Jusuf Nurkic added 18 points and 10 rebounds.
The Cavs, along with the Oklahoma City Thunder, are winless this season.
The Cleveland Cavaliers are bad without LeBron James - like, 0-wins bad - but that's not such a awful thing if you're a fan looking to score a REALLY cheap ticket last minute. Boston shot just 32 percent in the first half and missed all 11 of its 3-point attempts.
Griffin ranked second among the NBA's scoring leaders at 33.8 points per game heading into Friday's action after posting 26 points against the Cavaliers.
With Kobe Bryant watching from a courtside seat, the Lakers trailed by eight points with six minutes remaining before Lance Stephenson started a 15-2 rally with back-to-back three-pointers.
Ross kept the Magic within striking distance with 12 points on 5-for-7 shooting. It's a matter of one, two, three stops, that's it, and we just haven't done it yet.