Mr. Pompeo is expected to meet with Foreign Secretary Luis Videgaray, Foreign Secretary-designate Marcelo Ebrard, and departing President Enrique Peña Nieto. Numerous migrants may chose to stay in countries along the route, though the Mexican government is already preparing a response.
Tensions rose Thursday when an immigration activist who led a migrant caravan through Mexico last spring was arrested by federal police and immigration agents in Ciudad Hidalgo on the Mexican side of the border. President Trump warned this week that he will halt federal aid funding to the two nations if they do not act to stop the exodus.
Earlier this year, Trump's criticism turned a migrant caravan into a spectacle, with day-by-day media coverage of the journey.
The much talked about caravan of Central American migrants has been forced to turn around at the Mexico-Guatemala border.
He said the caravan is "not organic" and is being underwritten by political opponents of the Honduran leadership.
While Trump has threatened to deploy the military to the Mexico-U.S. border, Lt. Col. Jamie Davis said Thursday in a statement that the "Department of Defense has not been tasked to provide additional support".
The group of Salvadoreans, Hondurans and Guatemalans say they are fleeing violence and poverty.More news: LeBron: Lakers' chemistry isn't like instant oatmeal
His successor, Andres Manuel Lopez Obrador, takes office December 1. He has long pushed economic development as a way to keep people from migrating, and on Wednesday he reached out again.
The migrants also chanted: "We are not smugglers, we are immigrants". "Anyone who wants to work in our country will have help, will have a work visa", he pledged.
Since the president suspended his controversial family separation policy in June, illegal border crossings have skyrocketed. Honduran activists have said they would welcome such a move, as most is channelled to security forces who are accused of repression.
The Honduran migrant caravan heading to the USA, as it is stopped at the Guatemala-Mexico worldwide bridge in Ciudad Hidalgo, Mexico.
Trump took things up a notch, falsely accusing Democrats wanting "Open Borders" and leading the "assault on our country" by a "large flow of people, INCLUDING MANY CRIMINALS".
Honduran migrants rush across the border towards Mexico, in Tecun Uman, Guatemala, Friday, Oct. 19, 2018.
"It was predictable and also the election process is very close, so he is making a political calculation", he added.
Military officials instructed troops to alert border agents if they encountered migrants, rather than intervene themselves, except in cases of self-defense.
"We are going to the United States!" he said.