"We don't play Champions League or what?" said the German, whose side now top the table with a 100 per cent record after four matches and are widely seen as the main challengers to defending champions Manchester City.
Klopp hit back at the former Red Devils skipper by claiming that he did not understand how to concentrate exclusively on one competition when at a club like Liverpool, who are expected to compete on all fronts.
Pep Guardiola's side are odds-on favourites to win their second consecutive league title but Liverpool are considered their biggest challengers this season.
"That's what Jurgen Klopp does".
The Anfield outfit lost to Real Madrid in the Champions League final, a game that will be remembered for Gareth Bale's incredible overhead kick as well as the dirty tricks that Sergio Ramos played. His league leaders could put a real marker down if they can bag three points against Spurs.
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"It is clear, with numbers [from] games and all that stuff - we get so much information after a game, which you [the media] don't have - you see how players react in different situations".
"How do you prepare a game when you don't focus on it?" I don't want to be too critical because I don't know exactly how he said it but sitting in an office and talking about football is completely different to doing the job, to be honest.
Tottenham were tipped by many to challenge Manchester City and Liverpool for the title after winning 3-0 at Manchester United last month. I don't know exactly what it means but to focus on one competition can only be if maybe you are already out of the competition almost. "We play for Liverpool".
"It's absolutely no problem".
"It has to be in good shape when we get in it, and if it takes a little bit longer then it takes a little bit longer". I don't like the situation, because I don't like to say to Fabinho, who is full of energy and desire to play, to tell him he is not involved.
"The first four weeks we had the same lineup and we changed one position, but it was to get a good start to create a base".