While the women's final between Serena Williams and Naomi Osaka will go down as one of the most dramatic and eventful Grand Slam finals in history, Djokovic focused purely on the task at hand as he slugged it out with Juan Martin del Potro.
Novak Djokovic of Serbia celebrates a service break in the 3rd set against Juan Martin del Potro of Argentina in the men's final on day fourteen of the 2018 U.S. Open tennis tournament at USTA Billie Jean King National Tennis Center.
The Serbian outlasted the Argentine 6-3 7-6 (7-4) 6-3 in three hours and 15 minutes on Arthur Ashe Stadium in NY.
It's the Serb's 14th career Grand Slam singles title-tying Pete Sampras for third all time-and his second consecutive major win, as he triumphed at Wimbledon just two months ago.
It was only the second set dropped by the Argentine at the tournament.
From 40-0 down, Djokovic broke down his opponent with careful and precise ball striking, teasing the error out of the tentative Del Potro.
"I was hoping he's going to be here tonight but I want to say 'Pete, I love you, you're my idol, '" said the Serb.More news: Students, futsal players and a YouTube superstar - Denmark's 'Replacements' in pictures
Like the victorious Djokovic, Del Potro has had to overcome injury problems to get back to this stage.
He made no mistake in seeing it out and strolled into a one-set lead after 42 minutes.
In the years between toppling Roger Federer in the 2009 final and Sunday's match, del Potro almost quit tennis after undergoing four wrist surgeries, three of them on his left wrist, that left him in a deep depression and had him seriously weighing retirement.
Djokovic took just 42 minutes to win the opening set, taking it 6-3, and battled past Del Potro in an enthralling tie-break in the second which enabled him to hold the ascendancy.
In their first meeting in a Grand Slam final it was Del Potro, back at this stage for the first time since 2009, who won the coin toss and elected to receive under the Arthur Ashe Stadium roof with heavy rain falling in NY.
However, the despair on Sunday belonged to a teary del Potro, who was back in a grand slam final for the first time since his one and only title in NY in 2009.
The US Open Men's singles final will be shown LIVE on Star Sports Select 1 and Star Sports Select 1 HD at around 1.30 am IST.