Fellow Twitter users also exploded in anger at Trump's tweet, which was in delayed response to an interview Lemon conducted with James that aired Monday.
Trump resorted to childish name-calling in a Friday evening tweet in which he slammed the intelligence of both James and CNN anchor Don Lemon. Laker fans who spoke with Eyewitness News also felt the same way, often mentioning the school James opened and how he's impacted those kids' lives.
In his tweet, Trump insulted Lemon and then said that it's "not easy" to make James look smart.
Mike refers to Michael Jordan, suggesting that Donald Trump's allegiances lie with the former Chicago Bull in terms of the GOAT (greatest of all time) debate. Lemon nor James has responded to Trump's tweet.
He also said he might consider running for office if someone said to him he was the only person and that Trump would win if he didn't step up. He responded, "I don't think so", until Lemon brought up Trump as a possible opponent.
He's dividing us, and what I've noticed over the last few months is that he's kind of used sport to kind of divide us. "I'd never sit across from him".More news: Campus community urged to take precautions to avoid West Nile virus
That echoed comments he made in January that Trump had "given people and racism... an opportunity to be out and outspoken without fear". He unleashed a tweet following the racial violence in Charlottesville, Virginia, last August saying, "Hate has always existed in America". They're just playing a role. "Statues has nothing to do with us now!"
Despite this, there hasn't always been bad blood between Mr Trump and the three-time National Basketball Association champion. In 2013, he congratulated James on winning Athlete of the Year at the ESPYs and "a great guy".
James played for over a decade - and in two stints - with the Cleveland Cavaliers and delivered a title to the championship-starved region in 2016.
Trump, who bumbles through speeches and brags how he is unprepared, is clearly continuing his campaign of hatred and prejudice.