"I hope it's a record that somebody breaks, because it will mean they are dedicated to the cause", Harrison said in a statement. That's a unsafe condition that develops when a woman has rhesus-negative blood (RhD negative) and has a baby in her womb with RhD positive blood.
Despite once being quoted as saying that he had no plans to stop donating blood, Harrison made his 1,173rd - and last - donation on Friday, at a point where he had already exceeded Australia's age limit for blood donors.
"We encourage the partners and friends of all new mothers to think about donating blood, just one donation helps ensure someone has the chance to be a mother".
"Women have had multiple miscarriages and children born with brain damage", she said.
A man who has donated blood for 60 years gave his final blood donation earlier this week after saving countless children.More news: 'Avengers: Infinity War' stays strong with US$61 million third weekend
The drug works as an injection that prevents a pregnant woman's body from developing possibly harmful antibodies that could negatively affect her next baby.
HDN caused the death of thousands of babies in Australia before the researchers discovered Anti-D injection in the 60s.
According to CNN, doctors are unsure why Mr Harrison has this rare blood type, but they concluded that it might have been triggered from the transfusions he received while a teenager, after his operation, which saved his life.
The mother must have also been previously sensitised to RhD-positive blood.
James' blood was RHD negative with RHD positive antibodies. Now the Australia Red Cross Blood Services have started a three-year research project using his DNA to try to develop a solution.
This disease is now treatable with a medicine called anti-D immunoglobulin.