Found a new remedy for baldness


A new study reveals that researchers from the University of Manchester's Centre for Dermatology Research were able to find an osteoporosis drug that offers a stimulatory effect on human hair follicles, according to a report from Eurekalert.

However, Dr Hawkshaw said that further clinical trials will be needed to test the safety as well as effectiveness of the drug in people.

Finasteride only works for men and like minoxidil, it has side effects, is not available on the NHS and doesn't always work.

Both have modest side-effects and mostly generate disappointing outcomes. The project team discovered that CsA restricts a protein that when otherwise left alone, slows the growth of hair follicles. But don't get too excited: Although the study authors concluded that WAY-316606 has the "potential to treat human hair loss disorders", it has only been tested on hair samples - not on actual, living humans.

"Although our study was small, it provides crucial evidence that JAK inhibitors may constitute the first effective treatment for people with alopecia areata", said Dr Julian Mackay-Wiggan, associate professor at Columbia University and a dermatologist at New York-Presbyterian Hospital.

It was published in the journal, Public Library of Science Biology.

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The Osteoporosis drug proves to be a boon to stimulate the hair growth in follicles.

Baldness can be an unwanted and stressful change for both men and women, especially as options for treatment have been limited.

It started with a hunt for novel agents to treat male pattern baldness, it marked down few candidates that were recognized to have hair growth as a outcome owing to their other damaging effects.

'When the hair growth-promoting effects of CsA were previously studied in mice, a very different molecular mechanism of action was suggested; had we relied on these mouse research concepts, we would have been barking up the wrong tree'. The follicles quickly went into the active "anagen" phase of hair growth, and began sprouting hair.

Researchers started out by examining Cyclosporine A, a drug used to treat cancer and autoimmune disease which is known to cause some patients to experience excessive hair growth.