However, if he does come back in a month or so, it would leave sufficient time for the 26 year-old to be ready for Brazil's opening game in Group E of the World Cup, against Switzerland in Rostov on June 17.
Rudi Garcia's Marseille remain level on points with third-placed Lyon, who occupy the final Champions League spot, while Monaco are four points ahead of the chasing duo.
PSG manager Unai Emery said earlier on Friday that Neymar was "close to returning".
Things continued to get worse for Monaco too, Draxler capping off a standout showing by thumping home a late seventh to ensure that Paris made light work of Leonardo Jardim's men on their way to domestic glory.
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Monaco started with plenty of energy but nearly fell behind inside nine minutes when Cavani collected at the back post, only to drag his volley across the face of goal and wide.
Cavani then released Di Maria with a superb hooked pass from inside his own half and the Argentine raced clear before lifting an exquisite chip over the advancing Danijel Subasic.
It was 4-0 just before the 30-minute mark Lo Celso grabbed his second on the night by heading home Javier Pastore's cross.
Monaco pulled one back, Lopes latching on to Almamy Toure's cross from the right to score for the eighth consecutive time in Ligue 1 - a first in the French top flight since Shabani Nonda in 2003.
Falcao headed home on a corner to beat his own keeper and Draxler added another goal with a powerful shot after another Pastore cross from the right.
Earlier, Florian Thauvin struck a late victor as Marseille twice came from behind to beat struggling Troyes 3-2 and stay in the hunt for a Champions League place.