'It's tough for any club going to Anfield and always has been, ' he said.
Former Republic of Ireland global Keith Andrews will be this week's guest in the Boot Room as he takes a look back on his time in the Premier League.
The Senegal forward, 25, will likely line up alongside Roberto Firmino after the Brazilian learned he would face no disciplinary action over an altercation with Everton defender Mason Holgate during an FA Cup third-round tie last month.
Playmaker Manuel Lanzini, meanwhile, should be back for the game, having previously been linked with the Reds throughout the January transfer window.
Despite his heroics in Portugal, Mane has been the least prolific of Liverpool's current front three, with 12 goals to his name this season compared with 21 for Firmino and 30 for the outstanding Mohamed Salah.More news: Jennifer Lawrence to '60 Minutes': Nude scenes empowering
Liverpool will be at home at Anfield this weekend as the Reds look to get a win against West Ham United.
Only Nathaniel Clyne is out injured, so team selection will be tricky.
"But with the teams below them continuing to pick up surprise results, West Ham need to find three or four wins from somewhere so they don't get sucked back into trouble". Since David Moyes took the helm at West Ham, Marko Arnautovic has had his hand (or foot) in 10 Premier League goals (7 goals, 3 assists), which is more than any other West Ham player.
"We know we are going into the business end of the season, so we have been working them hard". We have a good position but a good position is only the basis for the next few games.
"Lanzini is an important player for us, but he has not played games", Moyes told a press conference.
Arthur Masuaku remains suspended after receiving a six-game ban for spitting.