Clubs can not play a team from the group from which they qualified until the quarter-finals, and likewise they are not allowed to meet a team from their own domestic league until the last eight either.
They topped Group A ahead of Basel, who clinched second place with a 2-0 victory over Benfica in Lisbon. They have won two, drawn two and lost one of their five games, scoring eight goals and conceding six times along the way.
This is a big week for United with City to come in the Premier League on Sunday and I can't see them making any mistakes midweek.
Powered by a front three of Neymar, Edinson Cavani and Kylian Mbappe, PSG had set a group-stage record of 24 goals before kick-off at the Allianz Arena, but were comfortably seen off by the five-time champions despite holding on to seal top spot in Group B.
Diego Simeone's team, twice a finalist in the last four years, must beat Chelsea away and needs Roma to draw or lose against Azerbaijani team Qarabag at home. The eight points they have means they are two clear of Atletico Madrid in third, and a win would be enough to send them through as the top side if Atleti beat Chelsea. It promises to be a cracking, passionate game between two of Europa's top clubs.
Germany's fourth team, Hoffenheim, didn't make the group stage after losing in the playoffs to Liverpool.More news: Stephen Curry on Crutches After Late-Game Ankle Injury
The move to their new Wanda Metropolitano stadium was created to herald a fresh period of success for Atletico Madrid, but Diego Simeone's side's streak of four straight runs to at least the Champions League last eight was abruptly ended.
PSG is seeking a sixth straight group win and to rebound from a shock 2-1 loss to promoted Strasbourg in the French league.
Tottenham and Manchester City had already qualified as group winners during the last round of group games, while United and Chelsea weren't assured of their finishing positions until tonight.
For Qarabag, this is a game they will relish playing in.
Tottenham are now top of Group H and as it stands will face Basel (20), Bayern Munich (4), *Juventus (5), *Sevilla (7), *Shakhtar Donetsk (16) or *Porto (12). For more tips from Michael read his column here. Spurs have won their last three CL games at Wembley 3-1 but I expect Spurs to keep a clean sheet in a comfortable win, which will end a wonderful group stage for the north London outfit.