Branden Grace on Sunday at the Gary Player Country Club, Sun City became the first South African to win the $7.5 million purse Nedbank Golf Challenge in a decade. Dubuisson then bogeyed the next, leaving the other two to effectively fight it out over the closing three holes.
Sinking to his knees, he bit the blade of his wedge in frustration and then had salt rubbed into his wounds as Grace produced his moment of magic to effectively claim an eighth European Tour title triumph at the age of 29.
Last year, Sweden's Alex Noren came from a similar shot deficit to win "Africa's Major" and Fleetwood will need to do the same.
"I'll take that for sure", said the 33-year-old whose only win on the European Tour came in 2013 at the now-defunct Nelson Mandela Championship at Royal Durban on the east coast.
"Hopefully you've always got something to play for towards the end of the year, whether it's top 30, gets you in The Open or Top-10, Race to Dubai, and it's a new experience trying to win it".
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South Africa's Haydn Porteous posted a five-under 67 to be at three-under, while Race to Dubai leader Tommy Fleetwood hit back after a hard first two days to also post a 67. "It feels nice to be able to finish the day off with a good round and I'm looking forward to the next couple days". Getting into Dubai was the goal coming here.
Victor Dubuisson was a shot further back from Grace's winning total of 11 under, while Li Haotong's stunning 64 saw the Chinese shoot up to fourth.
"There's still an terrible long way to go but if I can do what I did today, I'll be in with a good shout". In doing so, he now only has fellow Englishman Justin Rose and Spaniard Sergio Garcia as challengers in Dubai in the battle to be Europe's No 1 this season.
Cape Town - England's Jordan Smith has withdrawn from the Nedbank Golf Challenge, hosted by Gary Player, following the second round on Friday.
Grace made six birdies in a bogey-free round of 66. "Short game killed me all week".
He sits in a share of 14th spot, just two strokes off the Top 5, while he looks out of reach of the leader Scott Jamieson who is eight under par. "(It) just gets magnified towards the end of it".