Biden certainly hasn't been shy about criticizing the current president Donald Trump.
Biden added that he thought he was the most qualified person in 2016, but didn't run for president because he wasn't "prepared to be able to give my whole heart, my whole soul, and all my attention" to running. Biden's has become increasingly outspoken with his criticism of the President over the last month.
"Oprah, no woman or man should announce they're running for president unless they can answer two questions", Biden explained.
"Well, he is, but he is a great and gifted writer and he said, "Look Joe" - I had written another book before that for a while was on the best seller list 20 some years ago and I had forgotten how much time I had put in to write the book".
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"I spoke to someone close to Biden, [who] said if he's healthy, he's going for it in 2020".
"Clinton backers sent the signal that they would not stop at voting records and policies if I did get in the race", Biden reveals.
Reflecting on the tragedies that have befallen him personally as he wrote his forthcoming book, "Promise Me Dad: A Year of Hope, Hardship and Purpose", Biden said he recalled a conversation he had with his mother Catherine "Jean" Finnegan Biden just after the deaths of his wife and daughter in which she encouraged him to persevere.
"But anyway, yes, I understand", she said.
Biden doesn't explicitly mention Trump in the upcoming OWN interview, but he does expand on what he thinks a real leader should be. They play to their strengths and try to shore up their weaknesses. The full interview will air on The Ellen DeGeneres Show on Monday.