It had previously reported loud soundwaves caused by Israeli jets near the commercial passages in the Lebanese Mountains, followed by a deafening explosion that was heard near the Lebanese-Syrian border.
The Syrian Observatory for Human Rights, a Britain-based organization that reports on the war, said the air strike had targeted a military installation.
The Syrian army responded by firing surface-to-air missiles at the aircraft.
Homs is Syria's third-largest city.
Wednesday's strike hit a copper factory in the industrial town of Hisya, 35 km (21 miles) south of Homs and 112 km north of Damascus, SANA reported.More news: Indianapolis to host 2022 college football title game
Israel has not officially commented.
"Yet another aggression of Israel... shows that Israeli authorities are not satisfied with the state terrorism against the Arab population in occupied Palestine, Syria and Lebanon".
On Tuesday, Hamas's deputy political chief Saleh al-Arouri met with Hassan Nasrallah in Beirut, leader of Hezbollah, in discussion that focused on Israel's recent attack on the Gaza tunnel and the Egyptian-brokered Palestinian reconciliation process.
Aoun also said that he did "not think there will be war with Israel, because Israel would not win such a war".
In March, Defense Minister Avigdor Liberman threatened that if the Syrian military fired its air defenses at Israeli jets "we will destroy them without the slightest hesitation".