Kick-off is at 20:45 but we'll be bring you updates and bullid-up throughout the course of the day. Chris Coleman will be without Gareth Bale for this match but his squad did show that it is capable of winning games without its star player in its last match against Georgia. The Everton defender suffered a broken leg in the return fixture in Dublin in March after a tackle by Neil Taylor. And this is a completely different football.
For tonight's massive game, as reported by Wales Online going into the contest, Wales players requested for the anthem to be cut out after the first few lines while they were lining up. With Robbie Brady and James McClean back from suspension, both players were restored to the team.
Wales were beginning to lose some of their tempo and became restricted to long shots.
Shane Long is out of tonight's game between Ireland and Wales in Cardiff.
The game will be broadcast live on Sky Sports in the United Kingdom, you can see their TV schedule here.
Wales has been a very solid team in these qualifiers, now second in Group D with 17 points.More news: The Walking Dead and Fear TWD crossover event in the works
"I will really have to think about it and replay the game again".
In one of the most crucial matches of the final qualifying round, Wales will host Ireland. Serbia have booked a top-two finish - and a victory in their home game with Georgia will guarantee their place in Russian Federation.
Ireland now knew they just needed to see the game out while Wales, who knew a draw might be enough soon found out it would not as results elsewhere went against them. I want to score goals for my country but I'll keep believing and it will come. We have to do that - it's our strength.
"We changed the side to give us energy for a big game in Lille against Italy at the European Championships. That's the way it's set up".
Before a ball was kicked this week, Portugal were already assured of a playoff spot at worst and may yet overhaul 100 percenters Switzerland at the top of the Group B table if they beat them in Lisbon on Tuesday. Wales plays without Bale.
And automatic qualification for next summer's World Cup in Russian Federation is not yet out of the question either. However, the home side have not been beaten on their own soil since September 2013. "I felt it was always going to be like this".