Real Madrid forward Gareth Bale could miss both forthcoming Champions League ties against former employers Tottenham Hotspur following reports that his latest injury setback is likely to keep him sidelined for up to one month.
Brooks, aged 20, was called-up by Wales despite making only 15 appearances for Chris Wilder's side.
Wales are now second in qualifying Group D and are on course to qualify for the play-offs.
Wales drew 1-1 away to group leaders Serbia in June when Bale was suspended and Lawrence said: "He's a big loss, but that doesn't faze us".More news: Arsene Wenger Beat An Impressive Sir Alex Ferguson Record, Yesterday
Wales will be without their talisman for their final two 2018 World Cup qualifiers.
Only the group winners are guaranteed a place at the World Cup in Russian Federation next year. "I've spoken to him and the doctors".
Despite Bale's absence, Bradshaw could well be kept out of the starting line-up by Liverpool teenager Ben Woodburn.
In order to secure a play-off place, Wales would realistically need at least four points from the final two group games.
It's also important to note that Wales will travel to Georgia for their penultimate clash and they now do that without their best and most influential player.