Romero's family confirms the news through a statement given by Chris Roe, Romero's manager, as stated in a report by NBC News. His longtime producer partner, Peter Grunwald, said Romero's cancer was a "brief but aggressive battle".
In the letter released to the times they stated that Romero was surrounded by family and listening to the score of his favorite film "The Quiet Man".
Romero's most lasting contribution to pop culture came from his very first movie, the 1968 horror classic Night of the Living Dead. [VIDEO]The legendary director was also known for his zombie-kind of films.
Born in the Bronx, New York, in 1940 to a Cuban father and Lithuanian-American mother, Romero attended Carnegie Mellon University in Pittsburgh. You can see some of those below.
Night Of The Living Dead creator George Romero has died aged 77.More news: Hugh Jackman Cast as Scar in Disney's 'The Lion King'
Romero will always be remembered for helping to launch the zombie genre with series such as "The Walking Dead" paying homage to him and his huge contribution to the genre for more than 40 years. It's sequel, Dawn of the Dead (1978) was a cutting look at consumerism, and is largely the model for nearly all zombie films that followed.
Night of the Living Dead, along with being a classic film, reinvented the zombie genre, handing down rules about the undead that would stick for decades.
He is survived by his wife and daughter, who were by his side when he passed, according to Roe. He would later follow it up with 1985's Day of the Dead, 2005's Land of the Dead, 2007's Diary of the Dead, and 2009's Survival of the Dead. "George, there will never be another like you", Stephen King added.
Previous films had shown zombies as being living people who had been bewitched through voodoo.
Romero once told NPR's Arun Rath in an interview, "I have a soft spot in my heart for the zombies".