However, the five-time Wimbledon champion would face her greatest challenge in the semi-final against hometown favourite Johanna Konta. I really felt when I achieved the final in 2015, and I won the French Open, I could feel the difference between winning a Grand Slam and not winning.
Muguruza who has not missed a beat so far throughout Wimbledon started her campaign with a straight set victory over Ekaterina Alexandrova (6-2, 6-4).
And the Spaniard believes her own game has gone up another level since playing those first two Grand Slam finals.
Williams, a five-time champion who had been trying to become the oldest victor of a major in the Open era, had squandered two set points at 5-4 in the first set. Williams will look to make history against Garbine Muguruza on Saturday, hoping to wrap up an incredibly emotional month for her on a positive note.
Where can one watch the live streaming of the women's singles final of Wimbledon 2017 between Venus Williams and Garbine Muguruza?
When this Wimbledon lacked its customary empress, its women's singles event gained the description "wide-open" and had the chance to yield a final that would be weird, anonymous or even clunky. "It's something that is greater than me and obviously just my focus on my match and my performance, and trying to improve".More news: India to bat first after New Zealand win toss
"For me it's incredible to be here in another final, because it means a lot", the No.14 seed said. "I have to go out there and take it and play well".
"She didn't give me much chance to do something".
"Definitely I want to win, for sure", Muguruza said on Friday.
"But I think the longer the tournament went on, she got herself out of a couple of tough matches, tough situations and struggles maybe in the first couple of rounds, but the more the draw opened up, the more she feels like it's her time to shine".
Her success, however, revealed the scarcity of elite British women in tennis in recent years.
"I would sum up my whole Wimbledon experience as memorable. One more win would be fantastic", Williams said. Not that I'm doing something different, honestly. She was asked about that match the other day, in this, her 75th major championship. "Yeah, Serena did play her in a final". Maybe it's just her tournament to end the drought.
"I think that only strengthens my belief that if I'm ever in a position to be involved in a Slam for the full fortnight, that I will be able to keep myself in that mental and physical state to be able to deal with hopefully one day playing for a title", Konta said.