His departure after just over three months on the job came early Tuesday morning after a wave of weekend reports that the president was poised to shake up his senior West Wing staff amid a series of missteps and the Russian Federation scandal that has dominated the news cycle in recent weeks and could threaten the presidency.
"The reasons for my departure are personal, but it has been my great honor to serve President Trump and this administration", Dubke wrote.
Mr Dubke is the latest White House staffer to leave this administration as scrutiny intensifies over contacts Trump staffers may have had with Russian government officials during the campaign and transition period.
White House press secretary Sean Spicer will reportedly hold on to his position, until President Trump appoints a replacement, the BBC reports.
Dubke oversaw the White House communications office, which ran press and other outreach efforts.More news: Mize ties Langer for lead at Senior PGA at Trump course
Moscow has denied U.S. intelligence agencies' conclusion that it meddled in the campaign to try to tilt the election in Trump's favor.
He is also a founding partner of the strategic communications and public affairs firm, Black Rock Group.
"The Germans are bad, very bad".
Amid the recent speculation, reports have surfaced that Trump is looking at bringing on former confidantes, including former campaign operative Corey Lewandowski, and possibly FOX News journalists to help with communication strategy for an administration that has lurched from one crisis to the next since Inauguration Day.
In a tweet early on Tuesday, Trump shot back against the Russia probes, writing: "Russian officials must be laughing at the USA & how a lame excuse for why the Dems lost the election has taken over the Fake News".
It is being reported that White House Press Secretary Sean Spicer will keep his job.
German Chancellor Angela Merkel had some strong words this week when she suggested that Europe's relationship with Washington had shifted significantly and that "we in Europe have to take our fate into our own hands".
Trump is also struggling with his legislative agenda, as health care and tax reform initiatives remain behind schedule with several fiscal deadlines looming.