A 1-0 derby defeat at London rivals West Ham on Friday night nearly certainly handed the Premier League crown to Chelsea.
Fabregas admits he and his team-mates were pleased to see the Hammers' victory but wants focus back on the clash at Stamford Bridge against Boro, who will be relegated if they lose. Tottenham spent most of last season in second place, but faltered in mid to late May, and finished third.
It's "de-ja vu all over again" as Spurs saw their title hopes dashed in a weeknight clash against a London rival.
The Blues could even wrap the title up before Tottenham kick a ball again with wins over Middlesbrough at home, on Monday, and at West Brom on Friday.
A goal by Manuel Lanzini - his ninth in 14 London derbies - condemned Spurs to a costly defeat when they were hoping for a 10th successive league win to keep the pressure on leaders Chelsea.
"It may sound unusual, but the game we lost 3-2 at White Hart Lane in early November, we wanted to repeat it because we were really good in that game".More news: Pakistan to drag India to ICJ over Kashmir dispute
The result leaves Pochettino's side four points off the top spot with just three games left to play. 'We have to wait but are thinking that it will be hard to catch Chelsea.
"I think you all know that now it is more hard to try to catch Chelsea. We didn't show the same performance as against Arsenal". Liverpool could only draw with Southampton so now lead City by a point having played a game more, while United are four points adrift and look likely to have to rely on winning the Europa League if they are to qualify for the Champions League.
Tottenman trainer Mauricio Pochettino knows it would take nothing short of a miracle to wrench the title from Chelsea now.
"We deserved it, we played so well".
"We started the second half a little bit sloppy, we conceded in the space and the way we conceded the goal in this type of football, when you are fighting for the big things, you feel disappointed, " Pochettino said. - West Ham have kept three consecutive Premier League clean sheets for the first time since December 2015.