Kyle Hendricks (3-2) pitched six effective innings and drove in a run as Chicago improved to 22-5 in its last 27 games against Cincinnati.
Reds right-hander Blake Wood entered in relief and gave up three runs as a Baez had an RBI single, Lester hit a sacrifice fly and Ben Zobrist singled in another run.
"Defensively, tonight was not our best night", Price said.
MIAMI - Lance McCullers paid tribute to the late Jose Fernandez and pitched like him, allowing no earned runs for the third start in a row, and Houston beat Miami to complete a three-game sweep. He lowered his 2017 ERA to 3.35 on Wednesday.
Maddon became the eighth active manager with at least 1,000 wins.
Mark Rzepczynski took over and allowed Canha's first homer on a 3-2 pitch. "He knew that was right tonight, and that's a great game to build off of". The Cubs, meanwhile, are 20-6 in Lester's last 26 home starts, are 9-1 in his last 10 outings versus the Reds, and 4-0 in his last four home starts against Cincinnati.
Chicago outscored Cincinnati 25-15 in the series and has 23 wins in its last 28 games against the Reds. Anthony Rizzo had to stretch as far as he could go to bring in the throw. He walked in one run before giving up the grand slam to Baez as the Cubs opened a 5-0 lead. He walked three and struck out four while throwing 88 pitches.More news: US Falls to Finland, 2-0, in MWC Quarterfinals
Garrett only spent about a week in the minors after being sent down on May 7, making one two-inning appearances, and he's back to the bigs for his seventh major league start this afternoon. "It was a good effort at the end, but we made some mistakes on the front end of that game that cost us early". The Cubs remain home for three games against the NL Central-leading Milwaukee Brewers.
But Chicago was hardly through.
Darrell Ceciliani, recalled from Triple-A Buffalo on Tuesday, had a run-scoring double in the first and a two-run homer in the third before leaving with a left shoulder injury.
"Starting pitching drives the engine", Maddon said. Carl Edwards Jr. worked a flawless eighth and Wade Davis got three outs for his ninth save.
Garrity, a lifelong Cubs fan, worked for Heineken and was attending Tuesday night's game against the Cincinnati Reds with work colleagues and his wife, according to the report. "On the big screen, we didn't see it".
Philadelphia led 2-0 before Robinson Chirinos and Rougned Odor had consecutive two-out RBI singles off reliever Joely Rodriguez (1-2) in the fifth.