The American Action Network, a political non-profit aligned with House Speaker Ryan (R-WI), has reserved $500,000 of airtime for a TV commercial to air nationally and in Ryan's district, McClatchy reported.
Democrats aren't happy about the House Republican health care bill, but they are upbeat about the prospect of the measure serving as a millstone around GOP necks.
"We're keeping our word", Ryan said.
The spot directs viewers to call a number that connects to the Capitol switchboard.
One such group, Save My Care, is set to launch a six-figure ad campaign Monday targeting 24 Republicans who voted "yes" on the bill, which narrowly passed the House last week.
White House spokeswoman Sarah Huckabee Sanders expects the Senate to make changes, but keep the bill's main pillars.
"They are going to be living in the emergency rooms again", potentially driving up health care costs, Kasich predicted.
Ryan also cited a report from the Congressional Budget Office (CBO) saying reforms proposed by the AHCA was "in compliance with the Senate budget rules".
It would end enhanced federal funding for Medicaid expansion and curtail federal support for the overall Medicaid program, which provides coverage for more than 70 million people.
On Thursday, the American Health Care Act (AHCA) made it over the first hurdle when it passed the Republican-led House.More news: Syrian rebels, families start leaving Damascus neighborhood
Mr Obama defended his signature achievement in Boston on Sunday night while accepting the John F Kennedy Profile in Courage Award.
The bill has now been moved to the Senate, where GOP members are less eager to bow to pressure from the White House and have threatened to rewrite the bill. Chuck Schumer (D-N.Y.), the Senate minority leader, speaking at an unrelated news conference, also criticized the new health care bill, saying he was concerned the measure would make it more hard for Americans with pre-existing health conditions to find affordable coverage. "Let's make it easier for people to afford their insurance".
Democratic fundraising has surged to challenge vulnerable Republicans who backed the plan.
"It is my fervent hope and the hope of millions. such courage is still possible, that today's members of Congress regardless of party are willing to look at the facts and speak the truth, even when it contradicts party positions", he said.
House Republicans, including all four from Kansas, fulfilled a key campaign promise by advancing a bill Thursday that repeals much of the Affordable Care Act. Without protections for pre-existing conditions he fears he would have to close his law practice and find a job that offers a group insurance plan.
President Donald Trump urged Senate Republicans on Sunday to "not let the American people down", as the contentious debate over overhauling the US health care systems shifts to Congress' upper chamber, where a vote is potentially weeks, if not months, away.
"There are no cuts to the Medicaid program", Price said on CNN's "State of the Union".
Rep. Tom MacArthur (R-3rd Dist.), whose proposal on the state waivers led to approval of the Republican measure, said the Medicaid cuts are created to force states to try hold down health care costs.
What the bill does contain is cuts to Medicaid to the tune of $880 billion over 10 years, and tax credits for individual and family health insurance purchases.