The home leg in Germany was overshadowed by an attack on the Dortmund team bus as it headed to the stadium.
Thomas Tuchel: "We need to play well and I am convinced we are capable of doing it".
After being out of the game for six weeks with an injury, Reus made a sensational return last weekend scoring a dream goal in Dortmund's 3-1 win against Eintracht Frankfurt. Not a big difference in scores to be honest, but fact remains that Dortmund are playing an away match, with Monaco having the away goal advantage.
"We had a wonderful interaction with our fans whose instinct for such situations is probably second to none".
The Champions League match between Monaco and Borussia Dortmund will be broadcast on FS2. Dortmund now needed to score three times without reply just to force extra time but they did not manage to get one back until three minutes after the restart, Dembele tormenting Mendy on the right before his cutback was lashed home first-time by Reus.
The last time Fabinho did not play for Monaco, the French league leader was thrashed by Paris Saint-Germain 4-1 in the League Cup final this month. "Well, I suppose we could be in the final!"
Monaco and Dortmund have several young players, and with the transfer window looming upon us, there will be a lot of scouts at this game for sure.More news: Ex-girlfriend of Facebook murder suspect meets with victim's family
Apart from the long-term injured Mario Goetze, Andre Schuerrle and Sebastian Rode - as well as Marc Bartra, who was wounded in the bomb attack on the team bus - manager Thomas Tuchel has a full contingent to choose from.
Monaco Interior Minister Patrice Cellario told L'Equipe newspaper that local authorities will make sure Borussia players feel safe in the principality.
It was a frantic spell after Mbappe's opener, with Monaco's attacking midfielder Bernardo Silva heading straight at Burki from a good position and Dortmund's Nuri Sahin hitting the crossbar with a curling freekick. Both Tuchel and his players, led by Greek defender Sokratis, condemned UEFA's decision to hold the game so soon after the attacks.
The Ruhr side are trailing 2-3 from their first leg match.
"This early goal affected our confidence", Tuchel said.
Substitute Ousmane Dembele, who replaced Erik Durm during the first half, breathed new life into Dortmund and a rampaging run ended with Reus sweeping his cross beyond Monaco's Danijel Subasic.