Mauer entered the game 7 of 18 off Salazar.
Encarnacion, who homered in the Indians' first game of the season, had been held without a dinger in his last 12 games, a stretch of 56 plate appearances.
"It was good because I haven't been in a game long enough to get a rhythm in the past couple starts, so it was nice to be out there and feel the flow of the game a little bit, get up and down more than a couple times, just try to get back to competing and going as deep as I can into the game", Tomlin said.
Ramirez and Lindor have paced Cleveland's offense as the team waited for its pitching to match last year's run of quality outings. In his last start, Bauer got clobbered on eight hits and six runs with a pair of homers against the Tigers.
"He's been a blessing", Francona said of Ramirez. "Those opportunities when you don't get the runs you think that you should, especially when you've got a good pitcher on the mound". "He may not look like it in stature, but he's a force".
Meanwhile, the Twins are 5-2 in their last seven Thursday games, and 1-5 in their last six game fours of a series. He gave up eight hits and six runs (four earned). "You come home and are playing teams in your division".
Cleveland followed later with a win using the same formula it rode to the World Series a year ago. A team like Cleveland that can do a lot of things with switch-hitters and their bench, it's good to have as many weapons as you can, especially if they're all throwing the ball well. Leading the way heading into Wednesday was Max Kepler with 15 hits, seven runs and seven RBI.More news: Fox News fires Bill O'Reilly after sexual harassment accusations
Minnesota left six runners on in the first three innings, including leaving the bases loaded in the first.
Ramirez switched bats and then hit his fourth homer of the season in the third, a two-run shot deep to right that cleared the high wall in Minnesota.
"Fastball, I don't see it", Sano said. "So, we don't get too carried away when we win a couple, just like I hope we don't get too down when we lose a couple". The right-hander entered the day with an 18.47 ERA, but recovered from a slow start.
Cleveland's offense, which entered the night fifth in the American League in scoring, kept adding on. Hitting just.085 on the season, Buxton laid down a surprise bunt with two on and two outs in the fourth inning, but was thrown out by catcher Roberto Perez to end the threat.
"It was a tough way to start", Hughes said. "That's how I know that I'm fixing it, when I get more walks because I'm taking less swings at bad pitches". That's the theme for all three of my starts so far. "Whether it's nine shutout or you give up six in an inning-and-two-thirds, you take it as it is and you move on the next day". Twins RHP Phil Hughes had his shortest outing since pitching two innings May 4, 2016, against Houston. Mejia rebounded from a rocky first start to strike out four in five innings last week.
They'll play again Thursday afternoon, and the Twins announced Ervin Santana would pitch that game opposite Trevor Bauer for the Indians. LHP Adalberto Mejia (0-1, 4.05) takes the ball for Minnesota.