A Mathiang layup with 15:58 remaining extended Louisville's lead to 45-36, but MI countered with a 10-4 run to close within 49-46 with 11:23 on the clock. And after Wagner's 3-pointer broke a 55-55 tie with 6:39 to go, the Wolverines led the rest of the way.
Michigan State did not fare as well against the top seed in their regional, the Spartans falling to Kansas 90-70.
Frank Mason III added 20 points for the top-seeded Jayhawks (30-4), who have advanced to the second weekend of the NCAA Tournament in nine of coach Bill Self's 14 seasons. The three point underdog Wolverines stormed back from an eight point deficit at the half behind a 45-33 run over the final 20 minutes. KU is also a 4.5-point favourite.
OR 75, Rhode Island 72: In Sacramento, Tyler Dorsey drained a 3-pointer with 11 seconds remaining to help third-seeded OR advance to the Sweet 16. Dorsey made 9 of 10 shots with four 3-pointers. He's averaging 16.4 points, 3.1 rebounds and 2.7 assists and hit a couple of game-winning shots in the regular season.
Sydney centre Isaac Humphries and his second-seeded Kentucky managed to fend off the tough 10th-seeded Wichita State 65-62 to set up a much-anticipated clash with third-seeded UCLA.
Duke was the preseason No. 1 team and seemed to have gained traction by winning four games in four days to capture the ACC tournament title.
Adebayo had 13 points and 10 rebounds.More news: May to trigger Brexit process on March 29
The victory extended Kentucky's winning streak to 13 and snapped Wichita State's 16-game winning streak.
And wipe tears away again, Shockers (31-5).
Australians were caught in a day of stunning second round upsets at the NCAA basketball tournament, with Louisville and Duke among the casualties and Kentucky surviving a thriller. The third-seeded Ducks are in a way Canada's team in the Big Dance, but they are slight Sports Interaction betting underdogs for Thursday's South Region matchup against No. 7 MI. The Ducks defense struggled early with the Rams leading 46-38 at the break before allowing 26 second half points to save their tournament lives.
The victory was a bit of revenge for the Wolverines (26-11), who were beaten 82-76 by Louisville in the 2013 NCAA Tournament championship.
Baylor were down with less than five minutes to go when scoreless guard Manu Lecomte erupted with 12 of Baylor's next 13 points.
Chimezie Metu scored 28 points and Bennie Boatwright added 16 for USC (26-10), which was trying to make its first Sweet 16 appearance since 2007.
The Wolverines, who have won seven straight games, defied odds to claim a conference title, prevailed in the first two games of the NCAA Tournament and are now a favorite against a higher seed in the Sweet 16. Take the points here - and go over the total - as OR advances to play Kansas for a trip to the Final Four.